L’urticaire chronique spontanee est une pathologie i nouveau en gali?re connue du grand public et de certains professionnels de sante.
A l’initiative du laboratoire Novartis et de l’association Asthme & Allergies, avec la participation du Groupe d’etudes ainsi que recherches en dermato-allergologie (GERDA) et du Groupe Urticaire en Societe francaise de dermatologie (GUS), une journee de sensibilisation se deroule en France le 3 octobre.
Lors une presentation a la presse de cette toute premiere journee par Novartis et Asthme & Allergies, 2 specialistes hospitaliers, le Pr Bouillet et le Dr Milpied, ont partage leur experience une gestion de l’urticaire, en particulier sous sa forme chronique. Cette forme reste trop souvent etiquetee “allergique” alors qu’il s’agit d’une inflammation chronique d’origine bien en gali?re connue, peut-etre auto-immune.
Temoignages et contribution d’individus atteintes d’urticaire
L’urticaire , une pathologie lequel pourra devenir chronique Le Pr Laurence Bouillet, du Centre national de Reference des Angioedemes (Clinique universitaire de medecine interne, CHU de Grenoble) et membre du GUS, a rappele qu’une urticaire (qui vient du commentaire ” ortie “), est une ” reaction epidermique fugace, qui dure moins de 24 heures “.
Cette reaction epidermique pourra survenir ponctuellement (12 a 20 % une population fera au moins une poussee d’urticaire dans sa vie) ou devenir chronique (0,5 a 1 % une population europeenne, avec davantage de femmes touchees et un pic entre 20 et 40 annees).
L’urticaire chronique spontanee, une maladie non allergique “evoluant via poussees” En France, le meme commentaire, “urticaire”, designe l’urticaire aigue et chronique, d’ou la nouvelle denomination https://datingmentor.org/fr/established-men-review/ proposee lorsque nos poussees durent environ 6 semaines : “urticaire chronique spontanee” (UCS).
Ces poussees ne semblent nullement de naissance allergique, meme s’il est en mesure de y avoir 1 contexte atopique (antecedents d’allergies).
Diverses facteurs declenchants ou favorisant ces poussees peuvent etre identifies par le patient, ou le medecin interogeant le patient : “dans 30 % des cas, une poussee est favorisee via le stress”, suivant le Pr Bouiller. D’autres facteurs vont pouvoir egalement influer sur les poussees, comme l’exposition au froid, au soleil, un travaux physique, une pression concernant les bras, votre contexte infectieux ou la prise de certains medicaments.
Cependant, dans un grand nombre de cas, on ne retrouve jamais l’element declenchant.
L’UCS : 2 types de symptomes et un dermographisme souvent associe Deux types de symptomes peuvent survenir lors des poussees. Ils sont enfile en evidence par l’interrogatoire, piece maitresse du diagnostic, explique le Pr Bouillet : – Plaques urticariennes (29 a 65 % des patients) – Angi?deme, ou angio-oedeme (1 a 13 % des patients) : c’est 1 ?deme des couches profondes d’une peau (hypoderme), qui apparait soudainement, reste localise, une couleur en peau, dure certains heures ou quelques temps et disparait totalement entre nos poussees.
Ces deux symptomes vont pouvoir etre associes (33 a 67 % des patients), comme chez une telle personne qui possi?de uploade les photos ci-dessous sur le site urticariaday.org :
Mes patients paraissent d’ailleurs invites avec nos experts de sante a leur montrer des photos de ces anomalies cutanees, souvent non presentes en consultation.
Un dermographisme cutane (lesion rouge et gonflee apparaissant plusieurs minutes apres stimulation de la peau) reste souvent associe a ces deux symptomes, et donc a rechercher.
Un impact multidimensionnel via la specialite de life Notre Dr Brigitte Milpied, dermatologue au CHU de Bordeaux et presidente du GERDA, souligne le “retentissement majeur de l’UCS sur la qualite de vie” (source des chiffres : Br J Dermatol. 1997) : – 63 % des patients presentent une anxiete polyfactorielle, incluant en particulier une incomprehension liee a un parcours : des patients ne savent pas votre qu’ils ont. Il leur a en general ete evoque au debut que c’etait allergique, d’ou la consultation d’allergologues, la realisation de tests, puis la consultation de dermatologues. Mes medecins ne sont pas forcement bien informes et “a l’aise” avec cette maladie, et cela expose a un parcours long avant le diagnostic, son explication et la prise en charge specifique important. – 38 % des patients rapportent une perturbation importante de leur sommeil (ils seront reveilles avec des demangeaisons, ou prurit). – 73 % des patients disent eviter les sorties, restaurants ou evenements sociaux. – Les patients subissent egalement Plusieurs restrictions au quotidien en raison de l’UCS : ceci perturbe le choix de leurs vetements (70 %), leur vie sexuelle (73 %), l’entretien en maison (49 a 71 %) mais aussi leur regime alimentaire (54 %), lorsqu’il un est conseille (et quelquefois mal explique) un regime “pauvre en histamino-liberateurs” (fromages fermentes, conserves, saucisson, etc. : cf. tableau 1 via cet article) A tel point que certains patients n’osent plus manger de multiples aliments, surtout si on leur a dit que “c’etait allergique”…
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